CRISPR/Cas9 gene editing special issue

Special Issue

Special Issue: Gene Conversion in Duplicated Genes

Gene conversion is an outcome of recombination, causing non-reciprocal transfer of a DNA fragment. Several decades later than the discovery of crossing over, gene conversion was first recognized in fungi when non-Mendelian allelic distortion was observed. Gene conversion occurs when a double-strand break is repaired by using homologous sequences in the genome. In meiosis, there is a strong pref...

Why a Special Issue on Gene Therapy?

Going both from the organism to the DNA and from the DNA to the organism, the biology of the 20th century has paved the way for a new type of biologist who has emerged from the laboratory during the last two decades: the gene therapist. At the beginning of the nineties, much of this young field was based on a relatively simple concept: a deficient function can be replaced with an artificial gen...

Special Issue

j Abstract After legislative changes in 1978, Italian psychiatry underwent a thorough overhaul, with the gradual closure of all Mental Hospitals. A nation-wide network of Departments of Mental Health now deliver outpatient and inpatient care, but also run semi-residential and residential facilities (the latter with 2.9 beds per 10,000 inhabitants). Hospital care is delivered through small psych...

Special issue.

It is with great pleasure that I introduce this specia l i s sue of Aging Successfully that focuses on Preventive Gerontology. Aging successfully is dependent on the individual himself or herself. While health professionals can act as a guide through life’s journey, it is only through one’s own efforts that the best outcomes can be assured. This issue provides tools that all of us can use to ag...